院長の論文・研究領域

【医師としての研究領域】

ヒト個体の発生メカニズムの遺伝的解明
精神疾患の染色体上疾患責任領域を染色体欠失、重複患者を用いて解明
精神疾患の発生機構とヒト遺伝子刷り込み現象の関係解明

【英文原著論文】

●代表論文（pdf）

Kandil E, Egashira M, Miyoshi O, Niikawa N, Ishibashi T, Kasahara M: The human gene encoding the heavy chain of the major histocompatibility complex class I-like Fc receptor (FCGRT) maps to 19q13.3. Cytogenet Cell Genet 73: 97-98, 1996.
Matsumoto N, Ohashi H, Kato R, Fujimoto M, Tsujita T, Sasaki T, Nakano M, Miyoshi O, Fukushima Y, Niikawa N: Molecular mapping of a translocation breakpoint at 14q13 in a patient with mirror-image polydactyly of hands and feet. Hum Genet 99: 450-453, 1997.
Egashira M, Ariga T, Kawamura N, Miyoshi O, Niikawa N, Sakiyama Y: Visible integration of the adenosine deaminase (ADA) gene into the recipient genome after gene therapy. Am J Med Genet 75: 314-317, 1998.
Miyoshi O, Hayashi S, Fujimoto M, Tomita H, Sohda M, Niikawa N: Maternal uniparental disomy for chromosome 14 in a boy with intrauterine growth retardation. J Hum Genet 43: 138-142, 1998
Sugio Y, Sugio Y, Kuwano A, Miyoshi O, Yamada K, Niikawa N, TsukaharaM: Translocation t(X;21)(q13.3; p11.1) in a Girl with Menkes Disease. Am J Med Genet 79: 191-194, 1998.
Miura K, Miyoshi O, Yun K, Inazawa J, Miyamoto T, Hayashi H, Masuzaki H, Yoshimura S, Niikawa N, Jinno Y, Ishimaru T: Repeat-directed isolation of a novel gene preferentially expressed from the maternal allele in human placenta. J Hum Genet 44: 1-9, 1999
Nakano M, Yoshiura K, Oikawa M, Miyoshi O, Yamada K, Kondo S, Miwa N, Soeda E, JinnoY, Fujii T, Niikawa N: Identification, characterization and mapping of the human ZIS (zinc-finger, splicing) gene. Gene 225: 59-65, 1998.
Miyoshi O, Kondoh T, Taneda H, Otsuka K, Matsumoto T, Niikawa N: 47,XX,upd(7)mat,+r(7)pat / 46,XX,upd(7)mat mosaicism in a girl with Silver-Russell syndrome (SRS): Possible exclusion of the putative SRS gene from a 7p13-q11 region.J Med Genet36: 326-329, 1999.
Fujii J, Hamaoka R, Matsumoto A, Fujii T, Yamaguchi Y, Egashira M, Miyoshi O, Niikawa N, Taniguchi N: The structural organization of the human aldehyde reductase gene, AKR1A1, and mapping to chromosome 1p32-p33. Cytogenet Cell Genet 84: 230-2, 1999.
Yamaguchi Y, Fujii J, Inoue S, Uozumi N, Yonagidani S, Ikeda Y, Egashira M, Miyoshi O, Niikawa N, Taniguchi N: Mapping of the human a1,6fucosyltransferase gene, FUT8, to human chromosome 14q24.3. Cytogenet Cell Genet 84: 58-60, 1999.
Hasuike S, Miura K, Miyoshi O, Miyamoto T, Niikawa N, Jinno Y, Ishikawa M: Isolation and localization of an IDDMK1,2-22-related human endogenous retroviral gene, and identification of a CA repeat marker at its locus. J Hum Genet 44(5): 343-7, 1999.
Soejima H, Miyoshi O, Yoshinaga H, Masaki Z, Ozaki I, Kajiwara S, Niikawa N, Matsuhashi S, Mukai T: Assignment of the programmed cell death 4 gene (PDCD4) to human chromosome band 10q24 by in situ hybridization. Cytogenet Cell Genet 87: 113-114, 1999.
Soejima H, Kawamoto S, Akai J, Miyoshi O, Arai Y, Morohka T, Matsuo S, Niikawa N, Kimura A, Okubo K, Mukai T: Isolation of NovelHeart-Specific Genes Using the BodyMap Database. Genomics 74: 115-120, 2001.
Miyoshi O, Yabe R, Wakui K, Koizumi S, Uchikawa M, Fukushima Y, Kajii T, Numakura C, Takahashi S, Hayasaka K, Niikawa N: Two Cases of Mosaic RhD Blood-Group Phenotypes and Paternal Isodisomy for Chromosome 1. Am J Med Genet 104: 250-256, 01, 2001.

【和文原著論文】

三好修、新川詔夫：歌舞伎メーキャップシンドローム.　領域別症候群シリーズ 15巻 317-319, 1996.
高井良美千代、神野智美、佐藤悦子、沼田早苗、高橋明子、庄野真由美、中村康寛、三好修：出生時まで生存した四倍体症例における発生機序の遺伝学的検討. 医学検査 50巻 2号 113-117, 2001
岡崎祐士、三好　修、原田雅典、原田誠一: 統合失調症はどこまでわかったか. 最新精神医学8巻3号 197-201, 2003
井上顕、北川洋史、三好　修、岡崎祐士：身体表現性障害概論. 別冊日本臨床　領域別症候群シリーズ、精神医学症候群1巻38号　2003

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